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TargetDNA polymerase beta
LigandBDBM50242090
Substrate/Competitorn/a
Meas. Tech.ChEMBL_550598
IC50 18600±n/a nM
Citation Prakash Chaturvedula VSHecht SMGao ZJones SHFeng XKingston DG New neolignans that inhibit DNA polymerase beta lyase. J Nat Prod 67:964-7 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
DNA polymerase beta
Name:DNA polymerase beta
Synonyms:DNA polymerase beta (Pol β)
Type:Protein
Mol. Mass.:38188.76
Organism:Homo sapiens (Human)
Description:n/a
Residue:335
Sequence:
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
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  Blast E-value cutoff:
BDBM50242090
n/a
NameBDBM50242090
Synonyms:2,4-Dimethoxy-5,6-methylenedioxy-1-(2-propenyl)benzene | CHEMBL469641
TypeSmall organic molecule
Emp. Form.C12H14O4
Mol. Mass.222.2372
SMILESCOc1cc(OC)c(CC=C)c2OCOc12
Structure
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