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TargetDNA polymerase beta
LigandBDBM50241922
Substrate/Competitorn/a
Meas. Tech.ChEMBL_550664
IC50 1300±n/a nM
Citation Massiot GLong CDavid BSerrano MJDaubié FAlby FAusseil FKnibiehler MMoretti CHoffmann JSCazaux CLavaud C Acylphloroglucinol derivatives from Mahurea palustris. J Nat Prod 68:979-84 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
DNA polymerase beta
Name:DNA polymerase beta
Synonyms:DNA polymerase beta (Pol β)
Type:Protein
Mol. Mass.:38188.76
Organism:Homo sapiens (Human)
Description:n/a
Residue:335
Sequence:
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
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  Blast E-value cutoff:
BDBM50241922
n/a
NameBDBM50241922
Synonyms:CHEMBL486991 | ddCTP SODIUM | sodium ((2S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl trihydrogentriphosphate
TypeSmall organic molecule
Emp. Form.C9H15N3O12P3
Mol. Mass.450.1501
SMILESNc1ccn([C@H]2CC[C@@H](COP([O-])(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)n1 |r|
Structure
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