| Reaction Details |
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 | Report a problem with these data |
| Target | DNA polymerase beta |
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| Ligand | BDBM50241930 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_550664 (CHEMBL1002759) |
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| IC50 | 342000±n/a nM |
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| Citation |  Massiot, G; Long, C; David, B; Serrano, MJ; Daubié, F; Alby, F; Ausseil, F; Knibiehler, M; Moretti, C; Hoffmann, JS; Cazaux, C; Lavaud, C Acylphloroglucinol derivatives from Mahurea palustris. J Nat Prod68:979-84 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA polymerase beta |
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| Name: | DNA polymerase beta |
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| Synonyms: | DNA polymerase beta (Pol β) | DPOLB_HUMAN | POLB |
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| Type: | Protein |
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| Mol. Mass.: | 38188.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 335 |
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| Sequence: | MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
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| BDBM50241930 |
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| n/a |
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| Name | BDBM50241930 |
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| Synonyms: | CHEMBL486194 | Mahureone E |
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| Type | Small organic molecule |
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| Emp. Form. | C32H48O6 |
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| Mol. Mass. | 528.7199 |
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| SMILES | [#6]-[#6]-[#6]-[#6](-[#6]-[#6](-[#8])=O)-[#6]1=[#6]2-[#8]-[#6](=O)-[#6](-[#6](=O)-[#6](-[#6])-[#6]-[#6])-[#6](=O)C2([#6]\[#6]=[#6](\[#6])-[#6])[#6]-[#6](-[#6]\[#6]=[#6](\[#6])-[#6])C1([#6])[#6] |c:8| |
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| Structure | 
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