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TargetDNA polymerase beta
LigandBDBM50250427
Substrate/Competitorn/a
Meas. Tech.ChEMBL_547030 (CHEMBL1036028)
IC50 1200±n/a nM
Citation Deng, JZStarck, SRLi, SHecht, SM (+)-Myristinins A and D from Knema elegans, which inhibit DNA polymerase beta and cleave DNA. J Nat Prod68:1625-8 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
DNA polymerase beta
Name:DNA polymerase beta
Synonyms:DNA Polymerase beta | DPOLB_RAT | Polb
Type:PROTEIN
Mol. Mass.:38334.34
Organism:Rattus norvegicus
Description:ChEMBL_1361926
Residue:335
Sequence:
MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGS
FRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQ
LPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
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  Blast E-value cutoff:
BDBM50250427
n/a
NameBDBM50250427
Synonyms:(+)-Myristinin D | CHEMBL448072
TypeSmall organic molecule
Emp. Form.C36H38O7
Mol. Mass.582.6827
SMILESOc1ccc(cc1)[C@@H]1C[C@H](c2ccc(O)cc2O1)c1c(O)cc(O)c(C(=O)CCCCCCCCc2ccccc2)c1O |r|
Structure
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