| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50240480 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_553112 (CHEMBL966142) |
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| Ki | 2000±n/a nM |
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| Citation |  Power, P; Di Conza, J; Rodríguez, MM; Ghiglione, B; Ayala, JA; Casellas, JM; Radice, M; Gutkind, G Biochemical characterization of PER-2 and genetic environment of blaPER-2. Antimicrob Agents Chemother51:2359-65 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | PER-2 beta-lactamase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33451.67 |
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| Organism: | Citrobacter freundii |
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| Description: | ChEMBL_553112 |
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| Residue: | 308 |
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| Sequence: | MNVITKCVFTASALLMLGLSSFVVSAQSPLLKEQIETIVTGKKATVGVAVWGPDDLEPLL
LNPFEKFPMQSVFKLHLAMLVLHQVDQGKLDLNQSVTVNRAAVLQNTWSPMMKDHQGDEF
TVAVQQLLQYSVSHSDNVACDLLFELVGGPQALHAYIQSLGVKEAAVVANEAQMHADDQV
QYQNWTSMKAAAQVLQKFEQKKQLSETSQALLWKWMVETTTGPQRLKGLLPAGTIVAHKT
GTSGVRAGKTAATNDAGVIMLPDGRPLLVAVFVKDSAESERTNEAIIAQVAQAAYQFELK
KLSAVSPD
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| BDBM50240480 |
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| n/a |
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| Name | BDBM50240480 |
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| Synonyms: | (2S,3S)-3-({(2Z)-2-(2-ammonio-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]ethanoyl}amino)-2-methyl-4-oxoazetidine-1-sulfonate | (2S,3S)-3-({(2Z)-2-(2-ammonio-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]ethanoyl}amino)-2-methyl-4-oxoazetidine-1-sulfonate(aztreonam) | 2-[1-(2-Amino-thiazol-4-yl)-1-((2S,3S)-2-methyl-4-oxo-1-sulfo-azetidin-3-ylcarbamoyl)-meth-(Z)-ylideneaminooxy]-2-methyl-propionic acid | AZTREONAM | Azactam | Azetreonam | CHEMBL158 | SQ-26776 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H17N5O8S2 |
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| Mol. Mass. | 435.433 |
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| SMILES | C[C@H]1[C@H](NC(=O)C(=N/OC(C)(C)C(O)=O)\c2csc(N)n2)C(=O)N1S(O)(=O)=O |r| |
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| Structure | 
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