| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sodium/glucose cotransporter 1 |
|---|
| Ligand | BDBM50242616 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_534075 (CHEMBL974294) |
|---|
| IC50 | 2.1±n/a nM |
|---|
| Citation |  Vernaleken, A; Veyhl, M; Gorboulev, V; Kottra, G; Palm, D; Burckhardt, BC; Burckhardt, G; Pipkorn, R; Beier, N; van Amsterdam, C; Koepsell, H Tripeptides of RS1 (RSC1A1) inhibit a monosaccharide-dependent exocytotic pathway of Na+-D-glucose cotransporter SGLT1 with high affinity. J Biol Chem282:28501-13 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sodium/glucose cotransporter 1 |
|---|
| Name: | Sodium/glucose cotransporter 1 |
|---|
| Synonyms: | High affinity sodium-glucose cotransporter | NAGT | Na(+)/glucose cotransporter 1 | SC5A1_HUMAN | SGLT1 | SLC5A1 | Sodium-dependent glucose cotransporter 1 (SGLT1) | Sodium/glucose cotransporter 1 | Sodium/glucose cotransporter 1 (SGLT1) | Solute carrier family 5 member 1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 73503.78 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P13866 |
|---|
| Residue: | 664 |
|---|
| Sequence: | MDSSTWSPKTTAVTRPVETHELIRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFL
AGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIY
IKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLA
IFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAI
PTIVSDGNTTFQEKCYTPRADSFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQR
CLSAKNMSHVKGGCILCGYLKLMPMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVG
CTNIAYPTLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEK
ELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRV
NEPGAFWGLILGLLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFIT
IVVISLLTKPIPDVHLYRLCWSLRNSKEERIDLDAEEENIQEGPKETIEIETQVPEKKKG
IFRRAYDLFCGLEQHGAPKMTEEEEKAMKMKMTDTSEKPLWRTVLNVNGIILVTVAVFCH
AYFA
|
|
|
|---|
| BDBM50242616 |
|---|
| n/a |
|---|
| Name | BDBM50242616 |
|---|
| Synonyms: | CHEMBL485831 | QCP |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H22N4O5S |
|---|
| Mol. Mass. | 346.403 |
|---|
| SMILES | N[C@@H](CCC(N)=O)C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
