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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Squalene synthase | ||
| Ligand | BDBM50270299 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_520603 (CHEMBL959525) | ||
| IC50 | >1000±n/a nM | ||
| Citation |  Cammerer, SB; Jimenez, C; Jones, S; Gros, L; Lorente, SO; Rodrigues, C; Rodrigues, JC; Caldera, A; Ruiz Perez, LM; da Souza, W; Kaiser, M; Brun, R; Urbina, JA; Gonzalez Pacanowska, D; Gilbert, IH Quinuclidine derivatives as potential antiparasitics. Antimicrob Agents Chemother51:4049-61 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Squalene synthase | |||
| Name: | Squalene synthase | ||
| Synonyms: | Farnesyltransferase, putative | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 47117.40 | ||
| Organism: | Leishmania major | ||
| Description: | ChEMBL_520603 | ||
| Residue: | 414 | ||
| Sequence: |
| ||
| BDBM50270299 | |||
| n/a | |||
| Name | BDBM50270299 | ||
| Synonyms: | (E)-3-[4'-(1'',3''-Dioxolanyl)-benzylidene]-quinuclidine | CHEMBL478912 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H21NO2 | ||
| Mol. Mass. | 271.3541 | ||
| SMILES | C1COC(O1)c1ccc(\C=C2\CN3CCC2CC3)cc1 |(30.99,-2.22,;29.45,-2.22,;28.97,-3.68,;30.22,-4.59,;31.46,-3.69,;30.22,-6.13,;31.54,-6.9,;31.55,-8.43,;30.21,-9.2,;30.21,-10.74,;28.88,-11.51,;28.88,-13.05,;27.53,-13.82,;26.2,-13.05,;26.2,-11.5,;27.53,-10.73,;26.81,-12.09,;28.29,-12.49,;28.88,-8.44,;28.88,-6.9,)| | ||
| Structure | 
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