| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosine-protein kinase Lck |
|---|
| Ligand | BDBM50099692 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_529613 (CHEMBL968351) |
|---|
| IC50 | 3800±n/a nM |
|---|
| Citation |  Chen, IJ; Chen, HL; Demetriou, M Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling. J Biol Chem282:35361-72 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tyrosine-protein kinase Lck |
|---|
| Name: | Tyrosine-protein kinase Lck |
|---|
| Synonyms: | 2.7.10.2 | LCK | LCK_HUMAN | LSK | Leukocyte C-terminal Src kinase | Lymphocyte cell-specific protein-tyrosine kinase | Lymphocyte-specific protein tyrosine kinase | P56-LCK | Protein YT16 | Proto-oncogene Lck | Proto-oncogene tyrosine-protein kinase LCK | Src/Lck kinase | T cell-specific protein-tyrosine kinase |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 57987.83 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P06239 |
|---|
| Residue: | 509 |
|---|
| Sequence: | MGCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGTLLIRNGSEVRDPLVTYEGSNPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKER
PEDRPTFDYLRSVLEDFFTATEGQYQPQP
|
|
|
|---|
| BDBM50099692 |
|---|
| n/a |
|---|
| Name | BDBM50099692 |
|---|
| Synonyms: | CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthren-2-yl)-2,2-dimethyl-propionamide | N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-dimethyl-propionamide | N-(9,10-dioxo-9,10-dihydrophenanthren-2-yl)-2,2-dimethylpropionamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H17NO3 |
|---|
| Mol. Mass. | 307.3432 |
|---|
| SMILES | CC(C)(C)C(=O)Nc1ccc-2c(c1)C(=O)C(=O)c1ccccc-21 |
|---|
| Structure | 
|
|---|
Search and Browse
