| Reaction Details |
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 | Report a problem with these data |
| Target | cGMP-dependent protein kinase |
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| Ligand | BDBM50182367 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_496992 (CHEMBL1005407) |
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| IC50 | 0.046±n/a nM |
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| Citation |  Scribner, A; Dennis, R; Lee, S; Ouvry, G; Perrey, D; Fisher, M; Wyvratt, M; Leavitt, P; Liberator, P; Gurnett, A; Brown, C; Mathew, J; Thompson, D; Schmatz, D; Biftu, T Synthesis and biological activity of imidazopyridine anticoccidial agents: Part II. Eur J Med Chem43:1123-51 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| cGMP-dependent protein kinase |
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| Name: | cGMP-dependent protein kinase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 112911.27 |
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| Organism: | Eimeria tenella |
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| Description: | ChEMBL_469577 |
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| Residue: | 1003 |
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| Sequence: | MGACSSKAQHQTRDPEPREQQAAQEQKSTGPSGAPNDAPAPAEAERKMSGSSATAPKGEM
PTASTGTPEQQQQQQQQQQQQQEQQQHPEHQQSEKQQQHGEEQQQERKPSQQQQNEEAAA
PHKHGGERKVQKAIKQQEDTQAEDARLLGHLEKREKTPSDLSLIRDSLSTNLVCSSLNDA
EVEALANAVEFFTFKKGDVVTKQGESGSYFFIVHSGEFEVIVNDKVVNKILTGQAFGEIS
LIHNSARTATIKTLSEDAALWGVQRQVFRETLKQLSSRNFAENRQFLASVKFFEMLTEAQ
KNVITNALVVQSFQPGQAIVKEGEKGDVLYILKSGKALVSIKNKEVRVLQRGEYFGERAL
LYDEPRSATITAEEPTVCVSIGRDLLDRVLGNLQHVLFRNIMLEALQQSKVFASFPTEQL
SRLIGSVVVKDYPENYIILDRENRTRASASALFSAQGVRFFFVLEGEVSVFAYKDKSSSS
SSSSSSSSSSSSAEGEMELHLIDTLKRGQAFGDEYVLSPNKPFAHCVKSNGPTKLALLTA
SALTATLGGQDIDETLDYNNKLAITKKMYIFRYLSEQQTQTLIKAFKTVRYTQGESIIRE
GEIGSRFFIIKLGEVVILKGEKRVRTLGRHDYFGERALLHDERRSATVAANSPEVDLWVV
DKDVFLQIVKGPMLTHLEERIRMQDTKVEFKDLNVVRVVGRGTFGTVKLVQHIPTQMRYA
LKCVSRKSVVALNQQDHIRLEREIMAENDHPFIIRLVRTFRDKEFLYFLTELVTGGELYD
AIRKLGLLGRYQAQFYLASIVLAIEYLHERNIAYRDLKPENILLDSQGYVKLIDFGCAKK
MQGRAYTLVGTPHYMAPEVILGKGYTLTADTWAFGVCLYEFMCGPLPFGNDAEDQLEIFR
DILAGKLIFPHYVTDQDAINLMKRLLCRLPEVRIGCSINGYKDIKEHAFFSDFDWDRLAG
RDLSPPLLPKGEIYAEDAEEGGLDIEEDEGIELEDEYEWDKDF
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| BDBM50182367 |
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| n/a |
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| Name | BDBM50182367 |
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| Synonyms: | 4-(2-(4-fluorophenyl)-7-(piperidin-4-yl)H-imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-amine | 4-[2-(4-Fluorophenyl)-7-piperidin-4-ylimidazo-[1,2-a]pyridin-3-yl]piperidin-2-ylamine | CHEMBL207476 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21FN6 |
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| Mol. Mass. | 388.4407 |
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| SMILES | Nc1nccc(n1)-c1c(nc2cc(ccn12)C1CCNCC1)-c1ccc(F)cc1 |
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| Structure | 
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