| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50265405 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_497294 (CHEMBL995856) |
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| Ki | 113±n/a nM |
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| Citation |  Mercer, SL; Shaikh, J; Traynor, JR; Matsumoto, RR; Coop, A Nitrile analogs of meperidine as high affinity and selective sigma-1 receptor ligands. Eur J Med Chem43:1304-8 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25266.54 |
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| Organism: | RAT |
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| Description: | Q9R0C9 |
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| Residue: | 223 |
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| Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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| BDBM50265405 |
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| n/a |
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| Name | BDBM50265405 |
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| Synonyms: | 1-Methyl-4-phenylpiperidine-4-carbonitrile | CHEMBL495954 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16N2 |
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| Mol. Mass. | 200.2795 |
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| SMILES | CN1CCC(CC1)(C#N)c1ccccc1 |
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| Structure | 
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