| Reaction Details |
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 | Report a problem with these data |
| Target | Lactoylglutathione lyase |
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| Ligand | BDBM7462 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_529831 (CHEMBL967534) |
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| IC50 | 20600±n/a nM |
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| Citation |  Takasawa, R; Takahashi, S; Saeki, K; Sunaga, S; Yoshimori, A; Tanuma, S Structure-activity relationship of human GLO I inhibitory natural flavonoids and their growth inhibitory effects. Bioorg Med Chem16:3969-75 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lactoylglutathione lyase |
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| Name: | Lactoylglutathione lyase |
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| Synonyms: | Aldoketomutase | GLO1 | Glx I | Glyoxalase 1 (GLO1) | Glyoxalase I | Ketone-aldehyde mutase | LGUL_HUMAN | Methylglyoxalase | S-D-lactoylglutathione methylglyoxal lyase |
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| Type: | Enzyme |
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| Mol. Mass.: | 20772.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q04760 |
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| Residue: | 184 |
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| Sequence: | MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQK
CDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNS
DPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKM
ATLM
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| BDBM7462 |
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| n/a |
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| Name | BDBM7462 |
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| Synonyms: | 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-chromen-4-one | CHEMBL150 | Kaempferol (18) | Kaempferol (Kmp) | cid_5280863 | kaempferol |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10O6 |
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| Mol. Mass. | 286.2363 |
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| SMILES | Oc1ccc(cc1)-c1oc2cc(O)cc(O)c2c(=O)c1O |
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| Structure | 
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