| Reaction Details |
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 | Report a problem with these data |
| Target | Chitinase B |
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| Ligand | BDBM10854 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_529989 (CHEMBL975905) |
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| IC50 | 3.4±n/a nM |
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| Citation |  Gouda, H; Yanai, Y; Sugawara, A; Sunazuka, T; Omura, S; Hirono, S Computational analysis of the binding affinities of the natural-product cyclopentapeptides argifin and argadin to chitinase B from Serratia marcescens. Bioorg Med Chem16:3565-79 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chitinase B |
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| Name: | Chitinase B |
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| Synonyms: | CHIB_SERMA | chiB |
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| Type: | Enzyme |
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| Mol. Mass.: | 55462.70 |
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| Organism: | Serratia marcescens |
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| Description: | P11797 |
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| Residue: | 499 |
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| Sequence: | MSTRKAVIGYYFIPTNQINNYTETDTSVVPFPVSNITPAKAKQLTHINFSFLDINSNLEC
AWDPATNDAKARDVVNRLTALKAHNPSLRIMFSIGGWYYSNDLGVSHANYVNAVKTPAAR
TKFAQSCVRIMKDYGFDGVDIDWEYPQAAEVDGFIAALQEIRTLLNQQTIADGRQALPYQ
LTIAGAGGAFFLSRYYSKLAQIVAPLDYINLMTYDLAGPWEKITNHQAALFGDAAGPTFY
NALREANLGWSWEELTRAFPSPFSLTVDAAVQQHLMMEGVPSAKIVMGVPFYGRAFKGVS
GGNGGQYSSHSTPGEDPYPNADYWLVGCDECVRDKDPRIASYRQLEQMLQGNYGYQRLWN
DKTKTPYLYHAQNGLFVTYDDAESFKYKAKYIKQQQLGGVMFWHLGQDNRNGDLLAALDR
YFNAADYDDSQLDMGTGLRYTGVGPGNLPIMTAPAYVPGTTYAQGALVSYQGYVWQTKWG
YITSAPGSDSAWLKVGRLA
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| BDBM10854 |
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| n/a |
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| Name | BDBM10854 |
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| Synonyms: | 4-[(1S,4R,10S,13S,16S,18R)-10-{3-[(acetamidomethanimidoyl)amino]propyl}-18-hydroxy-16-(1H-imidazol-4-ylmethyl)-3,9,12,15,20-pentaoxo-2,8,11,14,17-pentaazatricyclo[15.2.1.0^{4,8}]icosan-13-yl]butanoic acid | Argadin | CHEMBL445236 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H42N10O9 |
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| Mol. Mass. | 674.7054 |
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| SMILES | CC(=O)NC(=N)NCCC[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)[C@H](Cc2cnc[nH]2)N2[C@H](O)C[C@H](NC(=O)[C@H]3CCCN3C1=O)C2=O |r| |
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| Structure | 
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