| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome c oxidase subunit 1 |
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| Ligand | BDBM50229774 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_530100 (CHEMBL967598) |
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| IC50 | 157200±n/a nM |
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| Citation |  Erdélyi, P; Fodor, T; Varga, AK; Czugler, M; Gere, A; Fischer, J Chemical and biological investigation of N-hydroxy-valdecoxib: An active metabolite of valdecoxib. Bioorg Med Chem16:5322-30 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome c oxidase subunit 1 |
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| Name: | Cytochrome c oxidase subunit 1 |
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| Synonyms: | COI | COX1_SHEEP | COXI | MT-CO1 | MTCO1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57042.19 |
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| Organism: | Ovis aries |
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| Description: | ChEMBL_662814 |
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| Residue: | 514 |
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| Sequence: | MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVIVTA
HAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEA
GAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQ
TPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH
PEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVD
TRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLAN
SSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVG
VNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMIFIIWEAFASKR
EVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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| BDBM50229774 |
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| n/a |
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| Name | BDBM50229774 |
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| Synonyms: | CHEMBL254418 | N-Hydroxy-4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide monohydrate | N-hydroxy-4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide hydrate |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14N2O4S |
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| Mol. Mass. | 330.358 |
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| SMILES | Cc1onc(c1-c1ccc(cc1)S(=O)(=O)NO)-c1ccccc1 |
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| Structure | 
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