Reaction Details |
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Target | Melatonin receptor type 1B |
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Ligand | BDBM50260394 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_530193 (CHEMBL973056) |
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IC50 | 4000±n/a nM |
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Citation | Ettaoussi, M; Péres, B; Klupsch, F; Delagrange, P; Boutin, JA; Renard, P; Caignard, DH; Chavatte, P; Berthelot, P; Lesieur, D; Yous, S Design and synthesis of benzofuranic derivatives as new ligands at the melatonin-binding site MT3. Bioorg Med Chem16:4954-62 (2008) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Melatonin receptor type 1B |
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Name: | Melatonin receptor type 1B |
Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
Type: | Enzyme |
Mol. Mass.: | 40203.54 |
Organism: | Homo sapiens (Human) |
Description: | P49286 |
Residue: | 362 |
Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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BDBM50260394 |
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n/a |
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Name | BDBM50260394 |
Synonyms: | 5-MCA-NAT | 5-methoxycarbonylamino-N-acetyltryptamine | CHEMBL504585 | methyl 3-(2-acetamidoethyl)-1H-indol-5-ylcarbamate |
Type | Small organic molecule |
Emp. Form. | C14H17N3O3 |
Mol. Mass. | 275.3031 |
SMILES | COC(=O)Nc1ccc2[nH]cc(CCNC(C)=O)c2c1 |
Structure |
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