| Reaction Details |
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 | Report a problem with these data |
| Target | Gonadotropin-releasing hormone receptor |
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| Ligand | BDBM50261208 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_555922 (CHEMBL956658) |
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| Ki | 110±n/a nM |
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| Citation |  Betz, SF; Zhu, YF; Chen, C; Struthers, RS Non-peptide gonadotropin-releasing hormone receptor antagonists. J Med Chem51:3331-48 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gonadotropin-releasing hormone receptor |
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| Name: | Gonadotropin-releasing hormone receptor |
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| Synonyms: | GNRHR | GNRHR_HUMAN | GRHR | GnRH receptor | GnRH-R | Gonadotropin releasing hormone 1 (GnRHR1) | Gonadotropin-releasing hormone receptor | Gonadotropin-releasing hormone receptor (GnRH) |
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| Type: | Enzyme |
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| Mol. Mass.: | 37749.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30968 |
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| Residue: | 328 |
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| Sequence: | MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL
QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL
KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRM
IHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTR
VLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRL
SDPVNHFFFLFAFLNPCFDPLIYGYFSL
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| BDBM50261208 |
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| n/a |
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| Name | BDBM50261208 |
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| Synonyms: | (R)-6-(2,6-difluorobenzyl)-2-(2-amino-2-phenylethyl)-4-(3-methoxyphenyl)-1,2,4-triazine-3,5(2H,4H)-dione | CHEMBL494968 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H22F2N4O3 |
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| Mol. Mass. | 464.464 |
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| SMILES | COc1cccc(c1)-n1c(=O)c(Cc2c(F)cccc2F)nn(C[C@H](N)c2ccccc2)c1=O |r| |
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| Structure | 
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