| Reaction Details |
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 | Report a problem with these data |
| Target | Matrilysin |
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| Ligand | BDBM50260799 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_552274 (CHEMBL995604) |
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| Ki | 602±n/a nM |
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| Citation |  Subramaniam, R; Haldar, MK; Tobwala, S; Ganguly, B; Srivastava, DK; Mallik, S Novel bis-(arylsulfonamide) hydroxamate-based selective MMP inhibitors. Bioorg Med Chem Lett18:3333-7 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrilysin |
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| Name: | Matrilysin |
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| Synonyms: | MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 29681.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09237 |
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| Residue: | 267 |
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| Sequence: | MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
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| BDBM50260799 |
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| n/a |
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| Name | BDBM50260799 |
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| Synonyms: | CHEMBL497962 | N-hydroxy-2,3-bis(3-(trifluoromethyl)phenylsulfonamido)propanamide |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15F6N3O6S2 |
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| Mol. Mass. | 535.438 |
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| SMILES | ONC(=O)C(CNS(=O)(=O)c1cccc(c1)C(F)(F)F)NS(=O)(=O)c1cccc(c1)C(F)(F)F |
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| Structure | 
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