| Reaction Details |
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 | Report a problem with these data |
| Target | D-aspartate oxidase |
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| Ligand | BDBM50260722 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_556667 (CHEMBL958954) |
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| IC50 | >5000±n/a nM |
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| Citation |  Sparey, T; Abeywickrema, P; Almond, S; Brandon, N; Byrne, N; Campbell, A; Hutson, PH; Jacobson, M; Jones, B; Munshi, S; Pascarella, D; Pike, A; Prasad, GS; Sachs, N; Sakatis, M; Sardana, V; Venkatraman, S; Young, MB The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors. Bioorg Med Chem Lett18:3386-91 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D-aspartate oxidase |
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| Name: | D-aspartate oxidase |
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| Synonyms: | D-Aspartate Oxidase (DDO) | DASOX | DDO | OXDD_HUMAN |
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| Type: | Oxidoreductase |
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| Mol. Mass.: | 37543.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Recombinant human DDO expressed and purified from sf9 insect cells, was used in enzyme assays. |
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| Residue: | 341 |
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| Sequence: | MDTARIAVVGAGVVGLSTAVCISKLVPRCSVTIISDKFTPDTTSDVAAGMLIPHTYPDTP
IHTQKQWFRETFNHLFAIANSAEAGDAGVHLVSGWQIFQSTPTEEVPFWADVVLGFRKMT
EAELKKFPQYVFGQAFTTLKCECPAYLPWLEKRIKGSGGWTLTRRIEDLWELHPSFDIVV
NCSGLGSRQLAGDSKIFPVRGQVLQVQAPWVEHFIRDGSGLTYIYPGTSHVTLGGTRQKG
DWNLSPDAENSREILSRCCALEPSLHGACNIREKVGLRPYRPGVRLQTELLARDGQRLPV
VHHYGHGSGGISVHWGTALEAARLVSECVHALRTPIPKSNL
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| BDBM50260722 |
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| n/a |
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| Name | BDBM50260722 |
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| Synonyms: | 4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylic acid | CHEMBL453239 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12ClNO2 |
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| Mol. Mass. | 249.693 |
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| SMILES | OC(=O)c1cc(CCc2ccc(Cl)cc2)c[nH]1 |
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| Structure | 
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