| Reaction Details |
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 | Report a problem with these data |
| Target | Urokinase-type plasminogen activator |
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| Ligand | BDBM50092659 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_553536 (CHEMBL958719) |
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| IC50 | 200000±n/a nM |
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| Citation |  Congreve, M; Chessari, G; Tisi, D; Woodhead, AJ Recent developments in fragment-based drug discovery. J Med Chem51:3661-80 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Urokinase-type plasminogen activator |
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| Name: | Urokinase-type plasminogen activator |
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| Synonyms: | PLAU | U-plasminogen activator | UROK_HUMAN | Urokinase | Urokinase-type plasminogen activator (uPA) | Urokinase-type plasminogen activator/surface receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48528.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00749 |
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| Residue: | 431 |
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| Sequence: | MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQ
HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHN
YCRNPDNRRRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKII
GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG
RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL
PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML
CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR
SHTKEENGLAL
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| BDBM50092659 |
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| n/a |
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| Name | BDBM50092659 |
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| Synonyms: | 2-AMINO-5-HYDROXY-BENZIMIDAZOLE | 2-Amino-3H-benzoimidazol-5-ol | 2-amino-3H-benzo[d]imidazol-5-ol | CHEMBL126589 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H7N3O |
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| Mol. Mass. | 149.15 |
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| SMILES | Nc1nc2ccc(O)cc2[nH]1 |
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| Structure | 
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