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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50261087
Substrate/Competitorn/a
Meas. Tech.ChEMBL_552367 (CHEMBL1005957)
Ki 3±n/a nM
Citation Smith, TAYang, XWu, HPouw, BMatsumoto, RRCoop, A Trifluoromethoxyl substituted phenylethylene diamines as high affinity sigma receptor ligands with potent anti-cocaine actions. J Med Chem51:3322-5 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:Enzyme Catalytic Domain
Mol. Mass.:25266.54
Organism:RAT
Description:Q9R0C9
Residue:223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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  Blast E-value cutoff:
BDBM50261087
n/a
NameBDBM50261087
Synonyms:CHEMBL497338 | N-Methyl-2-piperidin-1-yl-N-{2-[2-(trifluoromethoxy)phenyl]-ethyl}ethanamine
TypeSmall organic molecule
Emp. Form.C17H25F3N2O
Mol. Mass.330.3884
SMILESCN(CCN1CCCCC1)CCc1ccccc1OC(F)(F)F
Structure
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