| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50260602 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_552367 (CHEMBL1005957) |
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| Ki | 6±n/a nM |
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| Citation |  Smith, TA; Yang, X; Wu, H; Pouw, B; Matsumoto, RR; Coop, A Trifluoromethoxyl substituted phenylethylene diamines as high affinity sigma receptor ligands with potent anti-cocaine actions. J Med Chem51:3322-5 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25266.54 |
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| Organism: | RAT |
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| Description: | Q9R0C9 |
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| Residue: | 223 |
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| Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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| BDBM50260602 |
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| n/a |
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| Name | BDBM50260602 |
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| Synonyms: | CHEMBL493369 | N-(4-(trifluoromethoxy)phenethyl)-N-methyl-2-(pyrrolidin-1-yl)ethanamine |
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| Type | Small organic molecule |
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| Emp. Form. | C16H23F3N2O |
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| Mol. Mass. | 316.3618 |
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| SMILES | CN(CCN1CCCC1)CCc1ccc(OC(F)(F)F)cc1 |
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| Structure | 
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