| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor gamma |
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| Ligand | BDBM50049240 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_556513 (CHEMBL956508) |
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| IC50 | 700±n/a nM |
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| Citation |  Sundriyal, S; Viswanad, B; Bharathy, E; Ramarao, P; Chakraborti, AK; Bharatam, PV New PPARgamma ligands based on 2-hydroxy-1,4-naphthoquinone: computer-aided design, synthesis, and receptor-binding studies. Bioorg Med Chem Lett18:3192-5 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor gamma |
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| Name: | Peroxisome proliferator-activated receptor gamma |
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| Synonyms: | Nr1c3 | PPARG_RAT | Pparg |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57562.54 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_642067 |
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| Residue: | 505 |
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| Sequence: | MGETLGDPPVDPEHGAFADALPMSTSQEITMVDTEMPFWPTNFGISSVDLSVMDDHSHSF
DIKPFTTVDFSSISAPHYEDIPFTRADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNRPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFINLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKVLQKMTDLRQIVTEHVQL
LHVIKKTETDMSLHPLLQEIYKDLY
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| BDBM50049240 |
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| n/a |
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| Name | BDBM50049240 |
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| Synonyms: | (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione | 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione | CHEMBL595 | PIOGLITAZONE | PIOGLITAZONE HYDROCHLORIDE |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20N2O3S |
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| Mol. Mass. | 356.439 |
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| SMILES | CCc1ccc(CCOc2ccc(Cc3sc(=O)[nH]c3O)cc2)nc1 |
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| Structure | 
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