Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetCannabinoid receptor 1
LigandBDBM50243862
Substrate/Competitorn/a
Meas. Tech.ChEMBL_554820
Ki>5000±n/a nM
Citation Pagé DBalaux EBoisvert LLiu ZMilburn CTremblay MWei ZWoo SLuo XCheng YXYang HSrivastava SZhou FBrown WTomaszewski MWalpole CHodzic LSt-Onge SGodbout CSalois DPayza KPayza K Novel benzimidazole derivatives as selective CB2 agonists. Bioorg Med Chem Lett 18:3695-700 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 1
Name:Cannabinoid receptor 1
Synonyms:CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:52868.96
Organism:Homo sapiens (Human)
Description:P21554
Residue:472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50243862
n/a
NameBDBM50243862
Synonyms:(S)-2-(4-ethoxybenzyl)-N,N-diethyl-1-((1-methylpyrrolidin-2-yl)methyl)-1H-benzo[d]imidazole-5-carboxamide | CHEMBL519592
TypeSmall organic molecule
Emp. Form.C27H36N4O2
Mol. Mass.448.6003
SMILESCCOc1ccc(Cc2nc3cc(ccc3n2C[C@@H]2CCCN2C)C(=O)N(CC)CC)cc1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: