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TargetCannabinoid receptor 2
LigandBDBM50244097
Substrate/Competitorn/a
Meas. Tech.ChEMBL_554821
EC50 4.2±n/a nM
Citation Pagé DBalaux EBoisvert LLiu ZMilburn CTremblay MWei ZWoo SLuo XCheng YXYang HSrivastava SZhou FBrown WTomaszewski MWalpole CHodzic LSt-Onge SGodbout CSalois DPayza KPayza K Novel benzimidazole derivatives as selective CB2 agonists. Bioorg Med Chem Lett 18:3695-700 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 2
Name:Cannabinoid receptor 2
Synonyms:CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:39690.94
Organism:Homo sapiens (Human)
Description:P34972
Residue:360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50244097
n/a
NameBDBM50244097
Synonyms:2-(4-ethoxybenzyl)-N-cyclohexyl-1-(cyclopropylmethyl)-N-methyl-1H-benzo[d]imidazole-5-carboxamide | CHEMBL453842
TypeSmall organic molecule
Emp. Form.C28H35N3O2
Mol. Mass.445.5964
SMILESCCOc1ccc(Cc2nc3cc(ccc3n2CC2CC2)C(=O)N(C)C2CCCCC2)cc1
Structure
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