| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50244319 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_554821 (CHEMBL953974) |
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| EC50 | 1.3±n/a nM |
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| Citation |  Pagé, D; Balaux, E; Boisvert, L; Liu, Z; Milburn, C; Tremblay, M; Wei, Z; Woo, S; Luo, X; Cheng, YX; Yang, H; Srivastava, S; Zhou, F; Brown, W; Tomaszewski, M; Walpole, C; Hodzic, L; St-Onge, S; Godbout, C; Salois, D; Payza, K; Payza, K Novel benzimidazole derivatives as selective CB2 agonists. Bioorg Med Chem Lett18:3695-700 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50244319 |
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| n/a |
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| Name | BDBM50244319 |
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| Synonyms: | 1-adamantan-1-ylmethyl-2-(4-ethoxy-benzyl)-1H-benzoimidazole-5-carboxylic acid diethylamide | CHEMBL511134 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H41N3O2 |
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| Mol. Mass. | 499.6868 |
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| SMILES | CCOc1ccc(Cc2nc3cc(ccc3n2CC23CC4CC(CC(C4)C2)C3)C(=O)N(CC)CC)cc1 |THB:19:20:23:27.18.26,19:18:21.20.25:23,26:18:21:25.24.23,26:24:21:27.19.18| |
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| Structure | 
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