Ki Summary

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Target

Calmodulin-sensitive adenylate cyclase

Ligand

BDBM50243792

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_492206 (CHEMBL951582)

IC50

>100000±n/a nM

Citation

Jimenez, ME; Bush, K; Pawlik, J; Sower, L; Peterson, JW; Gilbertson, SR Synthesis and screening of small molecule inhibitors of anthrax edema factor. Bioorg Med Chem Lett18:4215-8 (2008) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Calmodulin-sensitive adenylate cyclase

Name:

Calmodulin-sensitive adenylate cyclase

Synonyms:

CYAA_BACAN | cya

Type:

PROTEIN

Mol. Mass.:

92481.33

Organism:

Bacillus anthracis

Description:

ChEMBL_606615

Residue:

800

Sequence:

MTRNKFIPNKFSIISFSVLLFAISSSQAIEVNAMNEHYTESDIKRNHKTEKNKTEKEKFK
DSINNLVKTEFTNETLDKIQQTQDLLKKIPKDVLEIYSELGGEIYFTDIDLVEHKELQDL
SEEEKNSMNSRGEKVPFASRFVFEKKRETPKLIINIKDYAINSEQSKEVYYEIGKGISLD
IISKDKSLDPEFLNLIKSLSDDSDSSDLLFSQKFKEKLELNNKSIDINFIKENLTEFQHA
FSLAFSYYFAPDHRTVLELYAPDMFEYMNKLEKGGFEKISESLKKEGVEKDRIDVLKGEK
ALKASGLVPEHADAFKKIARELNTYILFRPVNKLATNLIKSGVATKGLNVHGKSSDWGPV
AGYIPFDQDLSKKHGQQLAVEKGNLENKKSITEHEGEIGKIPLKLDHLRIEELKENGIIL
KGKKEIDNGKKYYLLESNNQVYEFRISDENNEVQYKTKEGKITVLGEKFNWRNIEVMAKN
VEGVLKPLTADYDLFALAPSLTEIKKQIPQKEWDKVVNTPNSLEKQKGVTNLLIKYGIER
KPDSTKGTLSNWQKQMLDRLNEAVKYTGYTGGDVVNHGTEQDNEEFPEKDNEIFIINPEG
EFILTKNWEMTGRFIEKNITGKDYLYYFNRSYNKIAPGNKAYIEWTDPITKAKINTIPTS
AEFIKNLSSIRRSSNVGVYKDSGDKDEFAKKESVKKIAGYLSDYYNSANHIFSQEKKRKI
SIFRGIQAYNEIENVLKSKQIAPEYKNYFQYLKERITNQVQLLLTHQKSNIEFKLLYKQL
NFTENETDNFEVFQKIIDEK

BDBM50243792

n/a

Name

BDBM50243792

Synonyms:

3-(1H-indol-5-yl)-5,5-dimethylcyclohex-2-enone | CHEMBL503247

Type

Small organic molecule

Emp. Form.

C16H17NO

Mol. Mass.

239.3123

SMILES

CC1(C)CC(=O)C=C(C1)c1ccc2[nH]ccc2c1 |c:6|

Structure