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TargetCyclin-dependent kinase 2-associated protein 1
LigandBDBM50243332
Substrate/Competitorn/a
Meas. Tech.ChEMBL_491562 (CHEMBL944208)
IC50>100000±n/a nM
Citation Janetka, JWAlmeida, LAshwell, SBrassil, PJDaly, KDeng, CGero, TGlynn, REHorn, CLIoannidis, SLyne, PNewcombe, NJOza, VBPass, MSpringer, SKSu, MToader, DVasbinder, MMYu, DYu, YZabludoff, SD Discovery of a novel class of 2-ureido thiophene carboxamide checkpoint kinase inhibitors. Bioorg Med Chem Lett18:4242-8 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cyclin-dependent kinase 2-associated protein 1
Name:Cyclin-dependent kinase 2-associated protein 1
Synonyms:CDK2AP1 | CDKA1_HUMAN | CDKAP1 | DOC1
Type:PROTEIN
Mol. Mass.:12370.40
Organism:Homo sapiens (Human)
Description:ChEMBL_491562
Residue:115
Sequence:
MSYKPNLAAHMPAAALNAAGSVHSPSTSMATSSQYRQLLSDYGPPSLGYTQGTGNSQVPQ
SKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS
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BDBM50243332
n/a
NameBDBM50243332
Synonyms:1-(5-(4-(2-(diethylamino)ethoxy)phenyl)-3-((3-(hydroxymethyl)phenyl)carbamoyl)thiophen-2-yl)urea | CHEMBL452020
TypeSmall organic molecule
Emp. Form.C25H30N4O4S
Mol. Mass.482.595
SMILESCCN(CC)CCOc1ccc(cc1)-c1cc(C(=O)Nc2cccc(CO)c2)c(NC(N)=O)s1
Structure
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