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TargetCyclin-dependent kinase 2-associated protein 1
LigandBDBM50243149
Substrate/Competitorn/a
Meas. Tech.ChEMBL_491562 (CHEMBL944208)
IC50 5300±n/a nM
Citation Janetka, JWAlmeida, LAshwell, SBrassil, PJDaly, KDeng, CGero, TGlynn, REHorn, CLIoannidis, SLyne, PNewcombe, NJOza, VBPass, MSpringer, SKSu, MToader, DVasbinder, MMYu, DYu, YZabludoff, SD Discovery of a novel class of 2-ureido thiophene carboxamide checkpoint kinase inhibitors. Bioorg Med Chem Lett18:4242-8 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cyclin-dependent kinase 2-associated protein 1
Name:Cyclin-dependent kinase 2-associated protein 1
Synonyms:CDK2AP1 | CDKA1_HUMAN | CDKAP1 | DOC1
Type:PROTEIN
Mol. Mass.:12370.40
Organism:Homo sapiens (Human)
Description:ChEMBL_491562
Residue:115
Sequence:
MSYKPNLAAHMPAAALNAAGSVHSPSTSMATSSQYRQLLSDYGPPSLGYTQGTGNSQVPQ
SKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS
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BDBM50243149
n/a
NameBDBM50243149
Synonyms:1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(thiophen-3-yl)thiophen-2-yl)urea | CHEMBL520734
TypeSmall organic molecule
Emp. Form.C15H18N4O2S2
Mol. Mass.350.459
SMILESNC(=O)Nc1sc(cc1C(=O)N[C@H]1CCCNC1)-c1ccsc1 |r|
Structure
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