| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidine kinase, cytosolic |
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| Ligand | BDBM50242983 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_492345 (CHEMBL948341) |
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| IC50 | 18000±n/a nM |
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| Citation |  Gerland, B; Désiré, J; Balzarini, J; Décout, JL Anti-retroviral and cytostatic activity of 2',3'-dideoxyribonucleoside 3'-disulfides. Bioorg Med Chem16:6824-31 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymidine kinase, cytosolic |
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| Name: | Thymidine kinase, cytosolic |
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| Synonyms: | KITH_HUMAN | TK1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25476.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1333884 |
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| Residue: | 234 |
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| Sequence: | MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
YSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVI
VAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADK
YHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
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| BDBM50242983 |
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| n/a |
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| Name | BDBM50242983 |
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| Synonyms: | 2',3'-Dideoxy-3'-(2-hydroxyethyldithio)thymidine | CHEMBL470689 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H18N2O5S2 |
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| Mol. Mass. | 334.412 |
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| SMILES | Cc1cn([C@H]2C[C@H](SSCCO)[C@@H](CO)O2)c(=O)[nH]c1=O |r| |
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| Structure | 
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