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TargetUrotensin II receptor
LigandBDBM50252239
Substrate/Competitorn/a
Meas. Tech.ChEMBL_487750
Ki 36±n/a nM
Citation Jin JAn MSapienza AAiyar NNaselsky DSarau HMFoley JJSalyers KLKnight SDKeenan RMRivero RADhanak DDouglas SA Urotensin-II receptor antagonists: synthesis and SAR of N-cyclic azaalkyl benzamides. Bioorg Med Chem Lett 18:3950-4 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Urotensin II receptor
Name:Urotensin II receptor
Synonyms:G-protein coupled receptor 14 | UR-II-R | Urotensin-II
Type:Enzyme Catalytic Domain
Mol. Mass.:42159.71
Organism:Homo sapiens (Human)
Description:Urotensin-II UTS2R HUMAN::Q9UKP6
Residue:389
Sequence:
MALTPESPSSFPGLAATGSSVPEPPGGPNATLNSSWASPTEPSSLEDLVATGTIGTLLSA
MGVVGVVGNAYTLVVTCRSLRAVASMYVYVVNLALADLLYLLSIPFIVATYVTKEWHFGD
VGCRVLFGLDFLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKGYRKLLALGTWLLALLL
TLPVMLAMRLVRRGPKSLCLPAWGPRAHRAYLTLLFATSIAGPGLLIGLLYARLARAYRR
SQRASFKRARRPGARALRLVLGIVLLFWACFLPFWLWQLLAQYHQAPLAPRTARIVNYLT
TCLTYGNSCANPFLYTLLTRNYRDHLRGRVRGPGSGGGRGPVPSLQPRARFQRCSGRSLS
SCSPQPTDSLVLAPAAPARPAPEGPRAPA
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  Blast E-value cutoff:
BDBM50252239
n/a
NameBDBM50252239
Synonyms:(S)-N-(1-(3-methoxy-4-(piperidin-4-yloxy)phenethyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide | CHEMBL519629
TypeSmall organic molecule
Emp. Form.C25H31Cl2N3O3
Mol. Mass.492.438
SMILESCOc1cc(CCN2CC[C@@H](C2)NC(=O)c2ccc(Cl)c(Cl)c2)ccc1OC1CCNCC1 |r|
Structure
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