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TargetUrotensin II receptor
LigandBDBM50252198
Substrate/Competitorn/a
Meas. Tech.ChEMBL_487750
Ki 15±n/a nM
Citation Jin JAn MSapienza AAiyar NNaselsky DSarau HMFoley JJSalyers KLKnight SDKeenan RMRivero RADhanak DDouglas SA Urotensin-II receptor antagonists: synthesis and SAR of N-cyclic azaalkyl benzamides. Bioorg Med Chem Lett 18:3950-4 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Urotensin II receptor
Name:Urotensin II receptor
Synonyms:G-protein coupled receptor 14 | UR-II-R | Urotensin-II
Type:Enzyme Catalytic Domain
Mol. Mass.:42159.71
Organism:Homo sapiens (Human)
Description:Urotensin-II UTS2R HUMAN::Q9UKP6
Residue:389
Sequence:
MALTPESPSSFPGLAATGSSVPEPPGGPNATLNSSWASPTEPSSLEDLVATGTIGTLLSA
MGVVGVVGNAYTLVVTCRSLRAVASMYVYVVNLALADLLYLLSIPFIVATYVTKEWHFGD
VGCRVLFGLDFLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKGYRKLLALGTWLLALLL
TLPVMLAMRLVRRGPKSLCLPAWGPRAHRAYLTLLFATSIAGPGLLIGLLYARLARAYRR
SQRASFKRARRPGARALRLVLGIVLLFWACFLPFWLWQLLAQYHQAPLAPRTARIVNYLT
TCLTYGNSCANPFLYTLLTRNYRDHLRGRVRGPGSGGGRGPVPSLQPRARFQRCSGRSLS
SCSPQPTDSLVLAPAAPARPAPEGPRAPA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50252198
n/a
NameBDBM50252198
Synonyms:(S)-N-(1-(3-chloro-4-(piperidin-4-yloxy)phenethyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide | CHEMBL521418
TypeSmall organic molecule
Emp. Form.C24H28Cl3N3O2
Mol. Mass.496.857
SMILESClc1ccc(cc1Cl)C(=O)N[C@H]1CCN(CCc2ccc(OC3CCNCC3)c(Cl)c2)C1 |r|
Structure
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