| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor A |
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| Ligand | BDBM50049189 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_488660 (CHEMBL988350) |
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| Ki | 1.1±n/a nM |
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| Citation |  Wallinder, C; Botros, M; Rosenström, U; Guimond, MO; Beaudry, H; Nyberg, F; Gallo-Payet, N; Hallberg, A; Alterman, M Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships. Bioorg Med Chem16:6841-9 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor A |
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| Name: | Type-1 angiotensin II receptor A |
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| Synonyms: | AGTRA_RAT | ANGIOTENSIN AT1 | Agtr1 | Agtr1a | Angiotensin II AT1 | Angiotensin II AT1A | Angiotensin II receptor (AT-1) type-1 | At1a | Type-1A angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40910.53 |
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| Organism: | RAT |
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| Description: | ANGIOTENSIN AT1 AGTR1 RAT::P25095 |
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| Residue: | 359 |
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| Sequence: | MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVC
AFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSSAKKPASCFEVE
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| BDBM50049189 |
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| n/a |
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| Name | BDBM50049189 |
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| Synonyms: | 3-[4-(2-Ethyl-57-dimethyl-imidazo[45-b]pyridin-3-ylmethyl)-phenyl]-5-isobutyl-thiophene-2-sulfonic acid butyloxycarbonylamide(L-162313) | CHEMBL288174 | L-162313 | butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)phenyl)-5-isobutylthiophen-2-ylsulfonylcarbamate |
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| Type | Small organic molecule |
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| Emp. Form. | C30H38N4O4S2 |
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| Mol. Mass. | 582.777 |
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| SMILES | CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 |
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| Structure | 
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