| Reaction Details |
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 | Report a problem with these data |
| Target | Neutral cholesterol ester hydrolase 1 |
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| Ligand | BDBM50204483 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_557654 (CHEMBL961604) |
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| IC50 | >100000±n/a nM |
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| Citation |  DeMartino, JK; Garfunkle, J; Hochstatter, DG; Cravatt, BF; Boger, DL Exploration of a fundamental substituent effect of alpha-ketoheterocycle enzyme inhibitors: Potent and selective inhibitors of fatty acid amide hydrolase. Bioorg Med Chem Lett18:5842-6 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neutral cholesterol ester hydrolase 1 |
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| Name: | Neutral cholesterol ester hydrolase 1 |
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| Synonyms: | AADACL1 | KIAA1363 | NCEH1 | NCEH1_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45810.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_835312 |
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| Residue: | 408 |
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| Sequence: | MRSSCVLLTALVALAAYYVYIPLPGSVSDPWKLMLLDATFRGAQQVSNLIHYLGLSHHLL
ALNFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEEPLKRSVVYIHGGGWALA
SAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMV
DPGRICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNT
PILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNY
KPVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKR
LESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSYIKWLDQNL
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| BDBM50204483 |
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| n/a |
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| Name | BDBM50204483 |
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| Synonyms: | 7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-1-one | CHEMBL373606 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18F3NO2 |
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| Mol. Mass. | 325.3255 |
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| SMILES | FC(F)(F)c1cnc(o1)C(=O)CCCCCCc1ccccc1 |
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| Structure | 
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