| Reaction Details |
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 | Report a problem with these data |
| Target | Oxytocin receptor |
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| Ligand | BDBM50262272 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_513959 (CHEMBL974600) |
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| Ki | 232±n/a nM |
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| Citation |  Brown, A; Brown, L; Ellis, D; Puhalo, N; Smith, CR; Wallace, O; Watson, L Design and optimization of potent, selective antagonists of Oxytocin. Bioorg Med Chem Lett18:4278-81 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxytocin receptor |
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| Name: | Oxytocin receptor |
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| Synonyms: | OT-R | OXTR | OXYR_HUMAN | Oxytocin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42793.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Oxytocin OXTR HEK293::B2R9L7 |
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| Residue: | 389 |
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| Sequence: | MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
SASKKSNSSSFVLSHRSSSQRSCSQPSTA
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|
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| BDBM50262272 |
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| n/a |
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| Name | BDBM50262272 |
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| Synonyms: | 2-(4-(ethylthio)-2-methylphenyl)-5-(4-(6-methoxypyridin-3-yl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrazine | CHEMBL467546 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22N6OS |
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| Mol. Mass. | 418.515 |
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| SMILES | CCSc1ccc(c(C)c1)-c1cnc(cn1)-c1nnc(C)n1-c1ccc(OC)nc1 |
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| Structure | 
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