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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Vasopressin V1a receptor | ||
| Ligand | BDBM50262153 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_513958 (CHEMBL974599) | ||
| Ki | 28±n/a nM | ||
| Citation |  Brown, A; Brown, L; Ellis, D; Puhalo, N; Smith, CR; Wallace, O; Watson, L Design and optimization of potent, selective antagonists of Oxytocin. Bioorg Med Chem Lett18:4278-81 (2008) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Vasopressin V1a receptor | |||
| Name: | Vasopressin V1a receptor | ||
| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor | ||
| Type: | Receptor | ||
| Mol. Mass.: | 46820.18 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P37288 | ||
| Residue: | 418 | ||
| Sequence: |
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| BDBM50262153 | |||
| n/a | |||
| Name | BDBM50262153 | ||
| Synonyms: | 4-{2-[2-(3-Biphenyl-4-yl-5-methyl-[1,2,4]triazol-4-yl)-phenoxy]-ethyl}-morpholine | CHEMBL467154 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H28N4O2 | ||
| Mol. Mass. | 440.5368 | ||
| SMILES | Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1OCCN1CCOCC1 |(3.08,-26.59,;1.54,-26.43,;.77,-25.1,;-.74,-25.43,;-.89,-26.97,;-2.22,-27.75,;-2.21,-29.29,;-3.54,-30.07,;-4.87,-29.29,;-4.89,-27.76,;-3.56,-26.99,;-6.21,-30.07,;-7.54,-29.31,;-8.87,-30.08,;-8.87,-31.62,;-7.54,-32.39,;-6.2,-31.62,;.52,-27.58,;.54,-29.12,;-.78,-29.9,;-.76,-31.44,;.58,-32.19,;1.91,-31.4,;1.88,-29.86,;3.2,-29.06,;4.55,-29.81,;5.87,-29.01,;7.22,-29.76,;7.24,-31.29,;8.58,-32.04,;9.9,-31.25,;9.88,-29.71,;8.53,-28.95,)| | ||
| Structure | 
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