| Reaction Details |
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 | Report a problem with these data |
| Target | Luciferin 4-monooxygenase |
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| Ligand | BDBM50261868 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_509645 (CHEMBL1003973) |
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| IC50 | 560±n/a nM |
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| Citation |  Heitman, LH; van Veldhoven, JP; Zweemer, AM; Ye, K; Brussee, J; IJzerman, AP False positives in a reporter gene assay: identification and synthesis of substituted N-pyridin-2-ylbenzamides as competitive inhibitors of firefly luciferase. J Med Chem51:4724-9 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Luciferin 4-monooxygenase |
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| Name: | Luciferin 4-monooxygenase |
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| Synonyms: | LUCI_AQULA | Luciferase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60126.66 |
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| Organism: | Luciola lateralis |
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| Description: | ChEMBL_786225 |
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| Residue: | 548 |
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| Sequence: | MENMENDENIVYGPEPFYPIEEGSAGAQLRKYMDRYAKLGAIAFTNALTGVDYTYAEYLE
KSCCLGEALKNYGLVVDGRIALCSENCEEFFIPVLAGLFIGVGVAPTNEIYTLRELVHSL
GISKPTIVFSSKKGLDKVITVQKTVTAIKTIVILDSKVDYRGYQSMDNFIKKNTPQGFKG
SSFKTVEVNRKEQVALIMNSSGSTGLPKGVQLTHENAVTRFSHARDPIYGNQVSPGTAIL
TVVPFHHGFGMFTTLGYLTCGFRIVMLTKFDEETFLKTLQDYKCSSVILVPTLFAILNRS
ELLDKYDLSNLVEIASGGAPLSKEIGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDK
PGASGKVVPLFKAKVIDLDTKKTLGPNRRGEVCVKGPMLMKGYVDNPEATREIIDEEGWL
HTGDIGYYDEEKHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPNIFDAGVAGVPDPIAG
ELPGAVVVLEKGKSMTEKEVMDYVASQVSNAKRLRGGVRFVDEVPKGLTGKIDGKAIREI
LKKPVAKM
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| BDBM50261868 |
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| n/a |
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| Name | BDBM50261868 |
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| Synonyms: | CHEMBL512625 | N-[5-(4-Chorophenyl)pyridin-2-yl]benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C18H13ClN2O |
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| Mol. Mass. | 308.762 |
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| SMILES | Clc1ccc(cc1)-c1ccc(NC(=O)c2ccccc2)nc1 |
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| Structure | 
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