| Reaction Details |
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 | Report a problem with these data |
| Target | Aryl hydrocarbon receptor |
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| Ligand | BDBM50240990 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_510004 (CHEMBL1005597) |
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| Ki | 6.8±n/a nM |
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| Citation |  Aiello, S; Wells, G; Stone, EL; Kadri, H; Bazzi, R; Bell, DR; Stevens, MF; Matthews, CS; Bradshaw, TD; Westwell, AD Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). J Med Chem51:5135-9 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aryl hydrocarbon receptor |
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| Name: | Aryl hydrocarbon receptor |
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| Synonyms: | AHR_RAT | Ahr |
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| Type: | PROTEIN |
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| Mol. Mass.: | 96224.95 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_510004 |
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| Residue: | 853 |
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| Sequence: | MSSGANITYASRKRRKPVQKTVKPVPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVI
NKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRSRGQDQCRAQVRDWQDLQEGEFLLQAL
NGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQ
CTDSAQGVDETHGLPQPAVYYTPDQLPPENTAFMERCFRCRLRCLLDNSSGFLAMNFQGR
LKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDA
KGQLILGYTEVELCNKGSGYQFIHAADMLHCAESHIRMIKTGESGMTVFRLLAKHSRWRW
VQSNARLIYRNGRPDYIIATQRPLTDEEGREHLQKRSMTLPFMFATGEAVLYEISSPFSP
IMDPLPIRTKSNTSRKDWAPQSTPSKDSFHPNSLMSALIQQDESIYLCPPSSPAPLDSHF
LMDSMSECGSWQGSFAVASNEALLKHEEIRHTQDVNLTLSGGPSELFPDNKNNDLYSIMR
NLGIDFEDIRSMQNEEFFRTDSSGEVDFKDIDITDEILTYVQDSLNNSTLLNSACQQQPV
SQHLSCMLQERLQLEQQQQLQQQHPTQTLEPQRQLCQVEVPQHELGQKTKHMQVNGMFAS
WNPAPPVSFSCPQQERKHYSLFSGLQGTAQEFPYKSEVDSMPYTQNFAPCNQSLLPEHSK
GTQLDFPGRDFERSLHPNASNLEDFVSCLQVPENQRHGINSQSAMVSPQAYYAGAMSMYQ
CQAGPQHTPVDQMQYSPEIPGSQAFLSKFQSPSILNEAYSADLSSIGHLQTAAHLPRLAE
AQPLPDITPSGFL
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| BDBM50240990 |
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| n/a |
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| Name | BDBM50240990 |
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| Synonyms: | 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole | 5-fluoro-2-(3,4-dimethoxyphenyl)benzothiazole | CHEMBL373251 | NSC-721648 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12FNO2S |
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| Mol. Mass. | 289.325 |
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| SMILES | COc1ccc(cc1OC)-c1nc2cc(F)ccc2s1 |
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| Structure | 
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