| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50272294 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_510208 (CHEMBL1004824) |
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| EC50 | >10000±n/a nM |
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| Citation |  Hilfiker, MA; Zhang, D; Dowdell, SE; Goodman, KB; McAtee, JJ; Dodson, JW; Viet, AQ; Wang, GZ; Sehon, CA; Behm, DJ; Wu, Z; Carballo, LH; Douglas, SA; Neeb, MJ Aminomethylpiperazines as selective urotensin antagonists. Bioorg Med Chem Lett18:4470-3 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM50272294 |
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| n/a |
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| Name | BDBM50272294 |
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| Synonyms: | 1-(4-(3-chlorobenzoyl)-2-(pyrrolidin-1-ylmethyl)piperazin-1-yl)-2-((3,4-dichlorophenyl)(methyl)amino)ethanone | CHEMBL501468 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29Cl3N4O2 |
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| Mol. Mass. | 523.882 |
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| SMILES | CN(CC(=O)N1CCN(CC1CN1CCCC1)C(=O)c1cccc(Cl)c1)c1ccc(Cl)c(Cl)c1 |
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| Structure | 
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