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TargetBradykinin B1 receptor
LigandBDBM50272415
Substrate/Competitorn/a
Meas. Tech.ChEMBL_510231
Ki 500±n/a nM
Citation Chen JJQian WBiswas KViswanadhan VNAskew BCHitchcock SHungate RWArik LJohnson E Discovery of dihydroquinoxalinone acetamides containing bicyclic amines as potent Bradykinin B1 receptor antagonists. Bioorg Med Chem Lett 18:4477-81 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Bradykinin B1 receptor
Name:Bradykinin B1 receptor
Synonyms:B1 BRADYKININ | B1 bradykinin receptor | B1R | BK-1 receptor
Type:Enzyme
Mol. Mass.:40508.87
Organism:Homo sapiens (Human)
Description:P46663
Residue:353
Sequence:
MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLL
VFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKAN
LFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQA
VPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRC
GGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF
AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50272415
n/a
NameBDBM50272415
Synonyms:2-(1-(mesitylsulfonyl)-3-oxo-1,2,3,4-tetrahydronoxalin-2-yl)-N-(2-methoxyphenyl)acetamide | CHEMBL498679
TypeSmall organic molecule
Emp. Form.C26H27N3O5S
Mol. Mass.493.575
SMILESCOc1ccccc1NC(=O)CC1N(c2ccccc2NC1=O)S(=O)(=O)c1c(C)cc(C)cc1C
Structure
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