| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50272081 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_510434 (CHEMBL1003110) |
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| IC50 | 3.02±n/a nM |
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| Citation |  Balboni, G; Fiorini, S; Baldisserotto, A; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. J Med Chem51:5109-17 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | Mu-opioid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44729.40 |
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| Organism: | Cavia porcellus |
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| Description: | ChEMBL_510437 |
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| Residue: | 400 |
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| Sequence: | MDSGAVPGNASDCTDPFAQSTCSPAPSPGSWTNLSHLDGNLSDPCGPNRTDLVGSDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRNGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50272081 |
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| n/a |
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| Name | BDBM50272081 |
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| Synonyms: | 2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid phenylcarbamoylmethyl-amide | CHEMBL501451 | H-Dmt-Tic-Gly-NH-Ph |
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| Type | Small organic molecule |
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| Emp. Form. | C29H32N4O4 |
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| Mol. Mass. | 500.5888 |
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| SMILES | Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCC(=O)Nc1ccccc1 |r| |
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| Structure | 
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