| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 4 |
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| Ligand | BDBM50245371 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_513112 (CHEMBL973601) |
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| Ki | 2±n/a nM |
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| Citation |  Marinkovic, D; Tucci, FC; Tran, JA; Fleck, BA; Wen, J; Chen, C Structure-activity relationship studies on a series of piperazinebenzylalcohols and their ketone and amine analogs as melanocortin-4 receptor ligands. Bioorg Med Chem Lett18:4817-22 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 4 |
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| Name: | Melanocortin receptor 4 |
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| Synonyms: | MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36949.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32245 |
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| Residue: | 332 |
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| Sequence: | MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
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| BDBM50245371 |
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| n/a |
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| Name | BDBM50245371 |
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| Synonyms: | (2R)-1-(4-(2-(1-amino-3-methylbutyl)phenyl)piperazin-1-yl)-2-(bis(pyridin-2-ylmethyl)amino)-3-(2,4-dichlorophenyl)propan-1-one | CHEMBL505442 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H42Cl2N6O |
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| Mol. Mass. | 645.664 |
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| SMILES | CC(C)CC(N)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)N(Cc1ccccn1)Cc1ccccn1 |r| |
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| Structure | 
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