Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein phosphatase non-receptor type 6 | ||
| Ligand | BDBM50246668 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_557717 (CHEMBL963012) | ||
| IC50 | 710±n/a nM | ||
| Citation |  Zhang, YN; Zhang, W; Hong, D; Shi, L; Shen, Q; Li, JY; Li, J; Hu, LH Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities. Bioorg Med Chem16:8697-705 (2008) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein phosphatase non-receptor type 6 | |||
| Name: | Tyrosine-protein phosphatase non-receptor type 6 | ||
| Synonyms: | HCP | PTN6_HUMAN | PTP1C | PTPN6 | Protein tyrosine phosphatase SHP-1 (SHP-1) | Protein-tyrosine phosphatase 1C | Protein-tyrosine phosphatase SHP-1 | Src homology phosphatase 1 (SHP-1) | Tyrosine-protein phosphatase non-receptor type 6 | Tyrosine-protein phosphatase non-receptor type 6 (SHP1) | ||
| Type: | Protein | ||
| Mol. Mass.: | 67570.41 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P29350 | ||
| Residue: | 595 | ||
| Sequence: |
| ||
| BDBM50246668 | |||
| n/a | |||
| Name | BDBM50246668 | ||
| Synonyms: | 3-(benzo[d][1,3]dioxol-5-yl)-2-(5-((4aR,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicen-4a-yl)pentanamido)propanoic acid | CHEMBL507502 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C44H65NO6 | ||
| Mol. Mass. | 703.99 | ||
| SMILES | CC1(C)CC[C@]2(CCCCC(=O)NC(Cc3ccc4OCOc4c3)C(O)=O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1 |r,c:33| | ||
| Structure | 
| ||