| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50264895 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_496463 (CHEMBL1004594) |
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| Ki | 1.8±n/a nM |
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| Citation |  Aslanian, R; Zhu, X; Vaccaro, HA; Shih, NY; Piwinski, JJ; Williams, SM; West, RE Benzimidazole-substituted (3-phenoxypropyl)amines as histamine H3 receptor ligands. Bioorg Med Chem Lett18:5032-6 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_MOUSE | Hrh3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48560.37 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_988451 |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50264895 |
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| n/a |
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| Name | BDBM50264895 |
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| Synonyms: | 5-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-2-(pyridin-2-yl)-1H-benzo[d]imidazole | CHEMBL495698 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H27FN4O |
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| Mol. Mass. | 430.5172 |
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| SMILES | Fc1ccc2n(c(nc2c1)-c1ccccn1)-c1ccc(OCCCN2CCCCC2)cc1 |
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| Structure | 
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