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TargetTranscriptional activator protein LuxR
LigandBDBM50266234
Substrate/Competitorn/a
Meas. Tech.ChEMBL_543884 (CHEMBL1016859)
IC50 1300±n/a nM
Citation Geske, GDMattmann, MEBlackwell, HE Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators. Bioorg Med Chem Lett18:5978-81 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Transcriptional activator protein LuxR
Name:Transcriptional activator protein LuxR
Synonyms:LUXS_ALIF1 | luxR
Type:PROTEIN
Mol. Mass.:28527.37
Organism:Vibrio fischeri (strain ATCC 700601 / ES114)
Description:ChEMBL_543884
Residue:250
Sequence:
MNIKNINANEKIIDKIKTCNNNKDINQCLSEIAKIIHCEYYLFAIIYPHSIIKPDVSIID
NYPEKWRKYYDDAGLLEYDPVVDYSKSHHSPINWNVFEKKTIKKESPNVIKEAQESGLIT
GFSFPIHTASNGFGMLSFAHSDKDIYTDSLFLHASTNVPLMLPSLVDNYQKINTTRKKSD
SILTKREKECLAWASEGKSTWDISKILGCSERTVTFHLTNTQMKLNTTNRCQSISKAILT
GAINCPYLKN
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BDBM50266234
n/a
NameBDBM50266234
Synonyms:(S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluoromethylthio)phenyl)acetamide | CHEMBL458227
TypeSmall organic molecule
Emp. Form.C13H12F3NO3S
Mol. Mass.319.299
SMILESFC(F)(F)Sc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r|
Structure
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