| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50253585 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_538661 (CHEMBL1033059) |
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| Ki | 21.2±n/a nM |
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| Citation |  Paul, NM; Taylor, M; Kumar, R; Deschamps, JR; Luedtke, RR; Newman, AH Structure-activity relationships for a novel series of dopamine D2-like receptor ligands based on N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ol. J Med Chem51:6095-109 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50253585 |
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| n/a |
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| Name | BDBM50253585 |
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| Synonyms: | CHEMBL521648 | endo-8-(5-Methoxy-1H-indol-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25ClN2O2 |
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| Mol. Mass. | 396.91 |
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| SMILES | COc1ccc2[nH]cc(CN3C4CCC3CC(O)(C4)c3ccc(Cl)cc3)c2c1 |TLB:9:10:12.13:18.16.15,19:16:12.13:10,THB:17:16:12.13:10| |
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| Structure | 
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