| Reaction Details |
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 | Report a problem with these data |
| Target | Oxytocin receptor |
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| Ligand | BDBM50263860 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_535596 (CHEMBL987070) |
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| Ki | 190±n/a nM |
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| Citation |  Brown, A; Brown, L; Brown, TB; Calabrese, A; Ellis, D; Puhalo, N; Smith, CR; Wallace, O; Watson, L Triazole oxytocin antagonists: identification of aryl ether replacements for a biaryl substituent. Bioorg Med Chem Lett18:5242-4 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxytocin receptor |
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| Name: | Oxytocin receptor |
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| Synonyms: | OT-R | OXTR | OXYR_HUMAN | Oxytocin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42793.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Oxytocin OXTR HEK293::B2R9L7 |
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| Residue: | 389 |
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| Sequence: | MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
SASKKSNSSSFVLSHRSSSQRSCSQPSTA
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| BDBM50263860 |
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| n/a |
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| Name | BDBM50263860 |
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| Synonyms: | 5-(3-(4-ethoxy-3-(trifluoromethyl)phenyl)-5-(methoxymethyl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridine | CHEMBL521789 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H19F3N4O3 |
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| Mol. Mass. | 408.3744 |
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| SMILES | CCOc1ccc(cc1C(F)(F)F)-c1nnc(COC)n1-c1ccc(OC)nc1 |
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| Structure | 
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