| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase Fgr |
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| Ligand | BDBM50094895 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_535977 (CHEMBL987151) |
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| IC50 | 24000±n/a nM |
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| Citation |  Cozza, G; Gianoncelli, A; Montopoli, M; Caparrotta, L; Venerando, A; Meggio, F; Pinna, LA; Zagotto, G; Moro, S Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening. Bioorg Med Chem Lett18:5672-5 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase Fgr |
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| Name: | Tyrosine-protein kinase Fgr |
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| Synonyms: | FGR | FGR_HUMAN | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | Proto-oncogene c-Fgr | SRC | SRC2 | p55-Fgr | p58-Fgr | p58c-Fgr |
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| Type: | protein |
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| Mol. Mass.: | 59469.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09769 |
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| Residue: | 529 |
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| Sequence: | MGCVFCKKLEPVATAKEDAGLEGDFRSYGAADHYGPDPTKARPASSFAHIPNYSNFSSQA
INPGFLDSGTIRGVSGIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSL
SSGKTGCIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAY
SLSIRDWDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAP
CTIMKPQTLGLAKDAWEISRSSITLERRLGTGCFGDVWLGTWNGSTKVAVKTLKPGTMSP
KAFLEEAQVMKLLRHDKLVQLYAVVSEEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLV
DMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKF
PIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCP
PGCPASLYEAMEQTWRLDPEERPTFEYLQSFLEDYFTSAEPQYQPGDQT
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| BDBM50094895 |
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| n/a |
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| Name | BDBM50094895 |
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| Synonyms: | 1,4-diamino-9,10-anthraquinone | 1,4-diamino-anthraquinone | 1,4-diaminoanthracene-9,10-dione | CHEMBL86771 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10N2O2 |
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| Mol. Mass. | 238.2414 |
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| SMILES | Nc1ccc(N)c2C(=O)c3ccccc3C(=O)c12 |
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| Structure | 
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