| Reaction Details |
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 | Report a problem with these data |
| Target | C5a anaphylatoxin chemotactic receptor 1 |
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| Ligand | BDBM50266072 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_543906 (CHEMBL1019502) |
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| IC50 | 3±n/a nM |
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| Citation |  Blagg, J; Mowbray, C; Pryde, D; Salmon, G; Fairman, D; Schmid, E; Beaumont, K Small, non-peptide C5a receptor antagonists: part 2. Bioorg Med Chem Lett18:5605-8 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C5a anaphylatoxin chemotactic receptor 1 |
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| Name: | C5a anaphylatoxin chemotactic receptor 1 |
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| Synonyms: | C5AR | C5AR1 | C5AR1_HUMAN | C5R1 | C5a anaphylatoxin chemotactic receptor | C5a anaphylatoxin chemotactic receptor (C5aR) | C5a-R | CD_antigen=CD88 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39347.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21730 |
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| Residue: | 350 |
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| Sequence: | MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVW
VTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNM
YASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREE
YFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKT
LKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIY
VVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
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| BDBM50266072 |
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| n/a |
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| Name | BDBM50266072 |
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| Synonyms: | (+/-)-ethyl 2-(N-(1,4-dioxaspiro[4.5]decan-8-yl)-1-naphthamido)-3-(4-chlorophenyl)propanoate | CHEMBL465377 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H32ClNO5 |
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| Mol. Mass. | 522.032 |
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| SMILES | CCOC(=O)C(Cc1ccc(Cl)cc1)N(C1CCC2(CC1)OCCO2)C(=O)c1cccc2ccccc12 |
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| Structure | 
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