| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C5a anaphylatoxin chemotactic receptor 1 |
|---|
| Ligand | BDBM50275728 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_496808 (CHEMBL1008821) |
|---|
| IC50 | 1.5±n/a nM |
|---|
| Citation |  Blagg, J; Mowbray, C; Pryde, DC; Salmon, G; Schmid, E; Fairman, D; Beaumont, K Small, non-peptide C5a receptor antagonists: part 1. Bioorg Med Chem Lett18:5601-4 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C5a anaphylatoxin chemotactic receptor 1 |
|---|
| Name: | C5a anaphylatoxin chemotactic receptor 1 |
|---|
| Synonyms: | C5AR | C5AR1 | C5AR1_HUMAN | C5R1 | C5a anaphylatoxin chemotactic receptor | C5a anaphylatoxin chemotactic receptor (C5aR) | C5a-R | CD_antigen=CD88 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39347.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21730 |
|---|
| Residue: | 350 |
|---|
| Sequence: | MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVW
VTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNM
YASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREE
YFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKT
LKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIY
VVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
|
|
|
|---|
| BDBM50275728 |
|---|
| n/a |
|---|
| Name | BDBM50275728 |
|---|
| Synonyms: | CHEMBL486749 | N-(4-chlorophenethyl)-2-isobutyl-N-(1,4-dioxaspiro[4.5]decan-8-yl)benzamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H34ClNO3 |
|---|
| Mol. Mass. | 456.017 |
|---|
| SMILES | CC(C)Cc1ccccc1C(=O)N(CCc1ccc(Cl)cc1)C1CCC2(CC1)OCCO2 |
|---|
| Structure | 
|
|---|
Search and Browse
