| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50252829 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_539465 (CHEMBL1028961) |
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| Ki | 1.86±n/a nM |
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| Citation |  Jeong, LS; Pal, S; Choe, SA; Choi, WJ; Jacobson, KA; Gao, ZG; Klutz, AM; Hou, X; Kim, HO; Lee, HW; Lee, SK; Tosh, DK; Moon, HR Structure-activity relationships of truncated D- and l-4'-thioadenosine derivatives as species-independent A3 adenosine receptor antagonists. J Med Chem51:6609-13 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36643.73 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_479910 |
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| Residue: | 320 |
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| Sequence: | MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALAD
IAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRY
RTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMV
FFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFL
FALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILR
ACRLCQTSDSLDSNLEQTTE
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| BDBM50252829 |
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| n/a |
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| Name | BDBM50252829 |
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| Synonyms: | (2S,3S,4R,5R)-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyl-tetrahydrothiophene-2-carboxamide | CHEMBL522152 | N6-(3-Iodo-benzyl)-9-(5'-methylaminocarbonyl-4'-thiobeta-D-ribofuranosyl)adenine |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19IN6O3S |
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| Mol. Mass. | 526.351 |
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| SMILES | CNC(=O)[C@H]1S[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3cccc(I)c3)ncnc12 |r| |
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| Structure | 
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