| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50252724 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_539504 (CHEMBL1032313) |
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| Ki | 2.4±n/a nM |
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| Citation |  Oberdorf, C; Schepmann, D; Vela, JM; Diaz, JL; Holenz, J; Wünsch, B Thiophene bioisosteres of spirocyclic sigma receptor ligands. 1. N-substituted spiro[piperidine-4,4'-thieno[3,2-c]pyrans]. J Med Chem51:6531-7 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50252724 |
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| n/a |
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| Name | BDBM50252724 |
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| Synonyms: | 3-Methoxy-1-(3-phenylpropyl)-6,7-dihydrospiro[piperidine-4,4-thieno[3.2-c]pyran] | CHEMBL495311 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27NO2S |
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| Mol. Mass. | 357.51 |
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| SMILES | COC1Cc2sccc2C2(CCN(CCCc3ccccc3)CC2)O1 |
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| Structure | 
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